Prolonged immune signaling can switch from fighting cancer to helping tumors grow by triggering changes that suppress the immune attack.

Deep inside many tumors, the immune system builds miniature organs of its own. These aggregates of immune cells, known as ...

Researchers studying ageing in mice have found that a decline in chaperone-mediated autophagy (CMA), a cellular recycling process, helps “zombie cells” accumulate by weakening the immune system’s ...

In addition to their established role in fighting pathogens, certain maternal immune cells (neutrophils) can support early ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

A study published in the journal Nature Communications reports that immune system aging does not progress at a constant rate, but accelerates significantly around age 40 and after age 60, with gender ...

Zeroing in on "Zombification" Scientists can create zombie cells in the laboratory by exposing body cells to drugs that stop ...

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine on Monday for their collective work in the discovery of specialized immune cells that roam ...

Obviously our bodies change a lot as we age, and culturally we tend to focus on the ones we can see-wrinkles, weight gain, loss of muscle mass, etc. But the most dramatic alterations may be happening ...

New research in mice shows that age-related loss of Wnt signaling in intervertebral disc cells suppresses chemokine ...

After three patient deaths and the indefinite suspension of several clinical trials, questions exist about the potential future of CAR T-cell research for autoimmune diseases.