An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations.

The angiopoietin-Tie signaling pathway has long been known to be essential for the maturation and maintenance of healthy blood vessels. It stabilizes the vessel wall and regulates vascular growth ...

Our understanding of how cells interact with each other has been driven for decades by the central concept of ...

A new benchmark of pathway activity scoring methods in single-cell RNA-seq reveals that top-rank-window tools like AUCell and ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

For years, TFEB has been regarded as one of the most promising therapeutic targets for restoring the cell's ability to clear ...

A small protein known as p11 may play a much broader role in cellular signaling than previously thought. Researchers at ...

Explore how oncogenes and signaling pathways converge and diverge in cancer, shaping diagnostic and therapeutic strategies for personalized interventions. This convergence is accompanied by ...

Researchers show that restoring IGFBP5 reduces stem cell senescence and enhances periodontal bone regeneration through ...